Sure, a 12-speed bike can be used together with an 11-speed cassette while training indoors. The original video demonstrating this setup got various views suggesting that the viewers are interested in this setup. In the year of usage, there has not occurred any abnormal wear of the teeth of the cassette, though little scarring was noted. The used SRAM AXS Flattop chain is supposed to be quite resilient and no troubles concerning chain wear were reported. Also, switching to a 10 to 28 tooth cassette and readjusting the B screw helped to improve shift quality.